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Rehabilitation Practice and Science

Translated Title

退化性膝關節炎病人注射玻尿酸的生理功能療效評估：初步報告

Abstract

Osteoarthritis of the knee joints is one of the most disabling diseases among the elderly because it causes limitations affecting many daily activities, and this results a large economic burden on public health. According to the date from the Bureau of National Health Insurance in 2000, the total expenditure of money on total knee replacements due to osteoarthritis reached 2.63 billion dollars, which was the second place in all inpatient medical expenses.The natural course of osteoarthritis of the knee joints is a gradual degeneration. As a result, treatments are aimed at pain alleviation, improving the joint's range of motion and functioning, and improving the patient's quality of life. This study enrolled patients with osteoarthritis of the bilateral knee joints. Five hyaluronic acid (Unihylon Dispo) injections at weekly intervals into the bilateral knees were carried out. Outcome measures, including the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and tests for assessing physical functioning (knee range of motion, lower limb strength and the sit to stand test), were evaluated before and after the intervention on physical functioning.A total of 21 patients completed the study. There were statistically significant improvement in the WOMAC pain subscore, stiffness subscore and total score. There was also a trend towards improvement in the WOMAC physical function subscore. Among the various tests assessing physical functioning, there was a significant improvement in the knee flexion range of motion. However, stabilization phase duration and the total time for the sit to stand test were not significantly decreased.Overall, in patients with osteoarthritis of the knee joints, the intraarticular injection of hyaluronic acid resulted in an improvement in physical functioning and this support the use of hyaluronic acid when treating knee osteoarthritis. (Tw J Phys Med Rehabil 2012; 40(2): 77 - 83)

Language

Traditional Chinese

First Page

77

Last Page

83

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