•  
  •  
 

Rehabilitation Practice and Science

Translated Title

急性橫斷性脊髓炎病患合併血清素症候群：病例報告

Abstract

Numerous serotonergic drugs have been increasingly used in recent years to treat depression, pain, insomnia and obesity. However, concomitant use of these drugs may cause serotonin syndrome. The three main clinical features of serotonin syndrome are neuromuscular abnormalities, autonomic hyperactivity, and mental status changes. A wide variety of the clinical presentations range from: very mild symptoms such as tremor, diarrhea, muscle rigidity, or clonus, and hyperreflexia; to fatal consequences such as disseminated intravascular coagulation or multiple-organ failure. Symptoms resolve spontaneously after prompt discontinuation of the precipitating medication. The diagnosis is based on clinical presentation, history of medication, and resolution after discontinuing the causative agents.We reported a 27-year-old female patient with acute transverse myelitis, suspected to be the first episode of multiple sclerosis, complicated with T4 flaccid paraplegia, and lower motor neuron type neurogenic bladder. The patient began to develop clonus, diaphoresis, shivering, and fever episodes after fluoxetine and tramadol were administered for depression and neuropathic pain. The patient’s symptoms resolved rapidly after discontinuation of the above medications. No similar symptoms were found in the following year. This paper describes the clinical features of serotonin syndrome and reviewarticleed related literature.

Language

Traditional Chinese

First Page

58

Last Page

68

Download

Share

COinS