Associated Study between Dopamine DRD2 Gene Polymorphism and Finger Tapping Test

Authors

Wen-Hsuan Hou
Tai-Jui Chen

Translated Title

多巴胺DRD2基因多型性與手指輕敲測驗的相關性研究

Abstract

Neurotransmitter dopamine has relation with neuro-psychiatric disease, it also has effect on motor function for healthy individuals and also determines the outcome of rehabilitation for neuro-psychiatric disease patients. Finger Tapping Test (FTT), a neuro-psychological test, is thought to be associated with dopamine. Therefore, the goal of this study is to investigate the association relationship between dopamine genes polymorphism (DRD2 TaqI) and FTT. Method: We recruit healthy Han Chinese, age between 20 and 60 years old, having no neuro-psychiatric illness and family history for dopamine genes polymorphism (DRD2 TaqI) and FTT assessment. Result: Total 106 cases were enrolled in the study. Analysis the relationship between FTT and DRD2 gene polymorphism showed that A1/A2 genotype has higher score of finger tapping test than A1/A1 or A2/A2 genotype (p=0.031). Conclusion: Our results show that there is significant relationship between FTT and DRD2 gene polymorphism.

Language

Traditional Chinese

DOI Link

https://doi.org/10.6315/2009.37(4)04

First Page

245

Last Page

250

Recommended Citation

Hou, Wen-Hsuan and Chen, Tai-Jui (2009) "Associated Study between Dopamine DRD2 Gene Polymorphism and Finger Tapping Test," Rehabilitation Practice and Science: Vol. 37: Iss. 4, Article 4.
DOI: https://doi.org/10.6315/2009.37(4)04
Available at: https://rps.researchcommons.org/journal/vol37/iss4/4