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Rehabilitation Practice and Science

Translated Title

膝關節內注射玻尿酸對退化性膝關節炎患者臨床疼痛症狀及日常生活功能之效應

Abstract

Osteoarthritis (OA) is a slowly evolving articular disease that appears to originate in the cartilage and affects the underlying bone, soft tissues, and synovial fluid. This condition usually occurs late in life, principally affecting the large weight-bearing joints such as the knee. It is particularly disabling when the knees are affected, because it limits the ability to walk, to rise from a chair, and to use stairs.The treatment selections for OA knees include analgesic drugs, physiotherapy, intra-articular (IA) drug administration, and surgical total knee replacement. We chose IA hyaluronic acid injection as the treatment method as it was documented as a safe drug, and being at least as efficacious as a continuous treatment with naproxen for 26 weeks. In this study, clinical pain symptoms, and activities of daily living were assessed by using Lequesne's Index before and after IA knee hyaluronic acid injections in 25 patients with bilateral knee OA. One session of hyaluronic acid injection was given to both knees (weekly IA knee injections for a total of five weeks). Results revealed significant improvements in clinical pain symptoms, and performance of activities of daily living after the completion of IA knee hyaluronic acid injections. Therefore, we conclude that IA knee hyaluronic acid injections are effective in alleviating the clinical pain symptoms, and improving the deteriorated activities of daily living that were caused by knee osteoarthritis.

Language

English

First Page

111

Last Page

116

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