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Rehabilitation Practice and Science

Translated Title

膝骨性關節炎患者的髕股骨關節功能評量與理奎森氏指數之比較

Abstract

Numerous therapeutic approaches are currently used to treat knee osteoarthritis. The relative efficacy of these approaches to the treatment of individual knees with osteoarthritis is not well understood. The main reason is that therapeutic outcome studies in osteoarthritis had been impeded by the lack of an objective, reproducible method for grading osteoarthritis of individual knee in order to compare the severity of the osteoarthritis between the two different sides. The Lequesne index has been used in most therapeutic trials on osteoarthritis of weight bearing joints. However, the ability of the Lequesne index to assess the status of individual knees with osteoarthritis is limited. The Patellofemoral function scale can be applied to evaluate individual knee status directly to determine the severity of osteoarthritis in each knee. The object of our study was to determine whether the patellofemoral function scale could be a potential measurement of severity of disease and outcome in osteoarthritis for individual knees. In this study, the grade of articular cartilage defects was considered to reflect the severity of knee osteoarthritis. Plain knee radiographs and associated scoring methods have long been used to measure the severity of osteoarthritis in clinical trials. However, the poor resolution inherent with this approach has limited its sensitivity and specificity as an outcome measure. Thus, in this study, ultrasonography was used to evaluate knee surfaces with a linear 7.5 MHz transducer. Thirty patients with knee osteoarthritis were enrolled in the study. Assessment of patellofemoral function scale and Lequesne index were performed before sonographic evaluation. There was a highly significant correlation (p ＜ 0.001) between the patellofemoral function scale and the grade of articular cartilage defects of individual knee. In the worst knees, the Lequesne index was significant correlated (p ＜ 0.001) with both the patellofemoral function scale and the grade of articular cartilage defect. The Lequesne index was not, or only weakly, associated with the patellofemoral function scale and the grade of articular cartilage defects in the less affected knees. We conclude that the patellofemoral function scale should be considered for the relevant measurement of knee osteoarthritis outcome with respect to clinical purposes. We believe that this approach could become an effective measurement tool for assessing efficacy of established and evolving therapeutic agents used for rehabilitation of this disease.

Language

Traditional Chinese

First Page

11

Last Page

18

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