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Rehabilitation Practice and Science

Translated Title

以前列腺素E1作海線體注射治療脊髓損傷患者勃起障礙之初步經驗

Abstract

Sexual dysfunction with inadequate or poorly sustained erection is a common problem among spinal cord injured patients although reflex erection may be preserved in upper motor neuron lesion and lower motor neuron and psychogenic erection may be preserved in incomplete lesion respectively. Methods to restore erection, such as vaccum tumescense constriction therapy and penile prostheses may be useful but potentially have adverse effects. Recently, intracavernous injection of prostaglandin E1 has been found beneficial to patients with neurogenic erectile dysfunction.In our study, we administered intracavernous injection of prostaglandin E1 (PGE1), 15 μ g, to seven patients with neurogenic erectile dysfunction due to spinal cord injury from May 1991 to November 1991 at chang Gung Memorial Hospital. Full erections sustaining at least thirty minutes following injections of PGE1 were seen in all of these patients while ejaculation in three patients and conception in one case were noted. No priapism, systemic reaction, nor fibrosis of cavernous tissue or scar formation was observed after thirty injections. From this preliminary clinical study, intracavernous injection of PGE1 is effective to neurogenic erectile dysfunction after spinal cord injury.

Language

Traditional Chinese

First Page

49

Last Page

53

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