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Rehabilitation Practice and Science

Translated Title

脊椎橫截病人血壓、腎素及皮質醛酮之正位性反應

Abstract

Orthostatic stimulations were performed with a tilt table on 32 patients paralyzed by neurologically complete transections of the spinal cord, of whom 10 had cervical cord lesions and 22 had thoracolumbar cord lesions. The hemodynamic and hormonal responses were compared between the 2 groups. In patients with cervical transactions, a 43.1% reduction in systolic pressure, 52.9% reduction in diastolic pressure and 24.2% increase in heart rate were observed during head-up tilt. Eight (80%) of 10 cases had orthostatic hypotension. A 123.4% increase in plasma rennin activity was also found. On the contrary, patients with thoracolumbar transactions showed significantly less reduction in systolic pressure (11%) and diastolic pressure (5.2%), lower frequency of orthostatic hypotension (13.6%) and less increase in plasma rennin activity (43.8%) in response to head-up tilt. The findings suggest that the sympathetic nervous system regulating orthostatic blood pressure may be damaged while the rennin ngiotensin system is activated in patients with transactional spinal cord lesions. The derangement is more severe in patients with cervical cord transactions than those with thoracolumbar cord lesions.

Language

English

First Page

36

Last Page

43

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