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Rehabilitation Practice and Science

Translated Title

脊髓損傷病患心律不整風險與危險因子之探討

Abstract

Objective: To investigate the risk of cardiac arrhythmias among adults with spinal cord injury (SCI). Methods: This is a retrospective population-based matched cohort study. Data were derived from the National Health Insurance Research Database. This study identified all patients diagnosed with SCI from January 1, 2000 to December 31, 2013. Patients with SCI were categorized into the cervical SCI (C-SCI) and other SCI (O-SCI) groups according to the level of injury. The cumulative incidence of cardiac arrhythmias was compared between patients with C-SCI, those with O-SCI, and those without SCI. Cox proportional hazards regression model was used to assess the differences in the incidence of cardiac arrhythmias between C-SCI and O-SCI groups. Results: The cumulative incidence of arrhythmia was higher in the C-SCI group than the O-SCI group or non-SCI group (log-rank p <0.0001). The C-SCI group had a higher risk of arrhythmia than the O-SCI group (adjusted hazard ratio = 1.64(95% CI 1.29-2.08, p < 0.0001). Other factors associated with arrhythmia included age, hyperlipidemia, hypertension, and chronic obstructive pulmonary disease. The incidence rate ratios (IRR) of three different types of cardiac arrhythmia were significantly higher in the C-SCI group than in the O-SCI group (supraventricular arrhythmia IRR = 3.65, 95% CI 2.23-5.99; ventricular arrhythmia IRR = 5.00, 95% CI 1.10-22.82; other arrhythmia IRR = 4.15, 95% CI 3.17-5.45). Conclusions: Patients with C-SCI had a higher risk of cardiac arrhythmia than patients with O-SCI or those without SCI. We should monitor these patients more carefully to detect the occurrence of arrhythmia.

Language

English

First Page

113

Last Page

122

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