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Rehabilitation Practice and Science

Translated Title

酒癮相關性之中央橋腦髓鞘溶解症:病例報告

Abstract

Central pontine myelinolysis (CPM) characterizes demyelinolysis of the central basal pons without involving the nerve axon. The etiology and incidence are unclear. According to previous reports, CPM occurs most often in chronic alcoholism, followed by hyponatremia due to rapid correction of electrolyte imbalance. Clinical manifestations of CPM include consciousness disturbance, lethargy, impaired brain function, dysphasia, dysarthria, four limbs weakness, ataxia, decreased deep tendon reflex, hypotension and seizure. The treatment of CPM includes supportive management with enough nutrition intake and rehabilitation programs. Our casereport is a 47 year old male with the history of diabetics mellitus, hypertension and chronic alcoholism. He suffered from hiccup, slurred speech, ataxia of bilateral lower extremities, weakness and a tendency to choke on water, accompanied by consciousness disturbance. The neurological examination showed positive Bull’s eye signs, severe dysarthria with mild aphasia, decreased bilateral deep tendon reflex and ataxia. In a series of brain MRI images, the T2- weighted images showed hyperdensity signals in the central pons. Due to easy approach of MRI study while suspicion, CPM should not be misdiagnosed. This casereport seeks to provide a guide to pertinent treatment of CPM.

Language

Traditional Chinese

First Page

221

Last Page

226

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