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Rehabilitation Practice and Science

Translated Title

交感神經反射失養症的病生理學

Abstract

Reflex sympathetic dystrophy (RSD) usually develops in a limb after an injury. It is characterized by constant burning pain, allodynia, hyperalgesia, swelling, vasomotor and sudomotor changes. Once RSD is established, successful outcome depends upon early recognition and therapy. The therapies include sympathetic blockade, myofascial trigger point injection, physical therapy, oral corticosteroid, etc. Many hypotheses have been proposed to explain the mechanism responsible for RSD. However, no single hypothesis proposed to date explains all of the features of RSD. It has been recognized for decades that pain may in certain instances be dependent on sympathetic innervation of the area afflicted with pain. Sympathetically maintained pain (SMP), a term that describes the intimate interrelationship of pain and autonomic dysfunction, is recognized by many to be an aspect (or even a defining characteristic) of causalgia and RSD. It seems that alpha-1 receptors expressed on the terminals of sensory nerve fibers develops the capacity, when activated, to evoke pain. Further studies are needed to elucidate the pathogenesis of the RSD.

Language

Traditional Chinese

First Page

1

Last Page

11

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